Do you need a child-resistant closure?
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An arithmetic check against a published list, and the arithmetic is where people get it wrong.
Work it out in the finished product
The thresholds in 16 CFR 1700.14 are stated as percentages by weight in the household substance as sold, not in the raw material.
So the calculation is: raw material concentration x the amount you add, as a percentage of the batch.
Check every product in the range separately, and re-check on every reformulation and on any supplier change where the raw material strength might differ.
The thresholds
Sodium or potassium hydroxide: 2 percent or more by weight in liquid; 10 percent or more in dry forms such as granules, powder and flakes.
Methyl alcohol (methanol): 4 percent or more in liquid, other than in pressurized spray containers.
Sulfuric acid: 10 percent or more.
Turpentine: 10 percent or more in liquid.
Ethylene glycol: 10 percent or more in liquid.
Nonemulsion liquid furniture polish with 10 percent or more mineral seal oil or other petroleum distillates below 100 SUS, other than in pressurized spray containers.
Liquid kindling or illuminating preparations with 10 percent or more petroleum distillates below that viscosity.
The list is longer than this; these are the entries a cleaning products maker meets.
Worked example
A degreaser using sodium hydroxide supplied as a 50 percent solution, added at 5 percent of the batch.
50 percent x 5 percent = 2.5 percent in the finished product.
The threshold is 2 percent. This product requires child-resistant packaging.
Reduce the addition to 3.5 percent and the finished concentration is 1.75 percent, which is under. That is a formulation decision with a packaging consequence, and it should be made deliberately rather than discovered.
What to do if you are over
Specify a closure certified to the standard in 16 CFR 1700.15, tested by the protocol in 1700.20, and keep the supplier's documentation.
Match it to the bottle finish: the package as a whole has to perform, so the closure and the bottle are a tested pair rather than two parts.
And check the cautionary labeling at the same time, because a formula strong enough to cross this threshold almost certainly needs FHSA labeling too.