When it pays for itself
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Breakeven in this category is dominated by one thing, and it is not equipment.
Two kinds of cost
Fixed: equipment, insurance, registration, label artwork, a display unit design, and the minimum order quantities you were forced to buy.
Variable: the per-tube cost of components, formula and labor.
Contribution per tube is price minus variable cost. Breakeven is fixed cost divided by contribution.
The arithmetic
Suppose fixed costs of 2,000, equipment, insurance, artwork and the first label and tube minimums, and a contribution of 2.00 a tube at direct retail.
That is 1,000 tubes to break even.
At wholesale, with a contribution nearer 0.50, the same fixed cost needs 4,000 tubes. The channel changes the answer by a factor of four, which is the point of doing it per channel rather than once.
What the number usually says
That a market-stall business breaks even in a season and a wholesale business takes considerably longer but scales.
And that a second flavor does not share the fixed cost the way people assume, because each SKU carries its own label minimum.
The packaging problem
The largest fixed cost here is usually not equipment. It is the minimum order on labels and tubes, committed before the first sale and specific to a design you have not yet tested.
Which is the argument for paying a bad unit price on the first small run. It keeps the fixed cost low while the range is uncertain, and it means the inevitable first redesign costs hundreds rather than thousands.