Where the work happens
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Skincare needs less space than most manufacturing and more cleanliness than most home activities, and the gap between those two is where the decisions are.
What the space has to do
Provide cleanable surfaces, a heat source, water of suitable quality, and somewhere to store raw materials cool, dark and sealed. It does not need drainage, extraction, or a large footprint.
What it does need is to be a space where the product is not competing with other activity. There is no kill step after manufacture, so everything in the room is a potential route in.
Separation and surfaces
Non-porous, cleanable surfaces. Stainless or glass vessels rather than plastic where you can, because scratched plastic holds residue in places that cannot be cleaned.
Equipment that comes apart, because the parts that do not get dismantled are the parts that never get clean: pump bodies, gaskets, nozzle threads.
And genuine separation from food preparation, pets and general household traffic during a run.
Water, air and the things you cannot see
Water of appropriate quality, used fresh rather than standing. Air that is not full of dust from another activity. And a habit of covering vessels and containers whenever they are not actively being worked on.
The invisible risks are the real ones: a film in a funnel, a wet vessel left overnight, an open jar of butter on a shelf for a month.
Home, shared or rented
Home manufacturing is common and workable at small scale, and the constraints are usually local rather than federal: zoning and home occupancy rules govern whether manufacturing may happen where you live, regardless of what the product is.
A shared commercial kitchen is possible and brings a contamination question, since you do not control what else happens in the room. A small dedicated unit is the eventual answer and is usually driven by storage and by wanting a space that is only ever used for this.