Shipping it
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Skincare ships badly: heavy, breakable, and capable of leaking over everything else in the parcel. It is also mostly sold online.
Glass, liquid, and post
A 30 ml glass dropper bottle is a small heavy object with a mechanism on top, and at these order values carriage is a large share of the delivered cost.
The instinctive fix, moving to plastic, has a chemistry cost: plastic is a worse barrier and can absorb preservatives and fragrance out of the formula. So the shipping decision runs back into the formulation decision, as most decisions in this property do.
What a shipper has to survive
Drops onto a corner, compression, and hours of vibration. The failure mode is bottles striking each other or the box wall, so the answer is immobilization rather than cushioning: a molded insert or dividers that stop movement entirely beat any amount of loose void fill.
Then leakage. A dropper or pump that has not been tightened, or a rim with product on it, will weep in transit. Seal the closure properly and consider an inner bag for anything liquid, which turns a ruined order into a wiped bottle.
Temperature in transit
A parcel in a van in summer reaches temperatures that stress an emulsion, and one left on a doorstep in winter can freeze. Freeze-thaw cycling exists in the stability protocol precisely because this happens, and three to five cycles between −10 and +25 °C is what the product should have survived before you shipped it.
A product that separates on the customer's doorstep separated because it was never tested against the doorstep.
Cases for wholesale
Case count sets the wholesale minimum and the retailer's shelf replenishment unit. Six or twelve are the conventional counts and six lowers the barrier for a small shop to try you.
Whatever you choose, fix it before printing sell sheets and price lists, because the count appears on all of them and changing it later is a documentation exercise across every account.