Selling under your state's rules
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This is the layer with the most variation and the most misinformation, and it is where an acidified product diverges sharply from every other small food business.
Cottage food usually will not cover you
Cottage food programs let certain low-risk foods be made in a home kitchen and sold directly, typically with labeling conditions, channel limits and sometimes a sales cap.
Acidified foods are generally excluded, because the hazard is the reason the program exists. A producer planning around a cottage food exemption for a vinegar-based pepper sauce is usually planning around something that does not apply.
Confirm it for your state. That is a phone call and it is the most valuable call in this whole section.
What the state actually licenses
Depending where you are: the facility, the operator, or both. Inspections at some frequency. A fee. And in some states a separate registration for the specific products.
The state layer sits alongside the federal requirements rather than replacing them. Holding a state license does not substitute for a process filing, and having a process filing does not substitute for the state license.
Selling across a state line
Shipping to another state brings you squarely under federal requirements and may bring you under that state's rules as well. Many cottage-style exemptions are limited to in-state, in-person sales, which excludes shipping entirely.
So an online shop is not a marketing decision, it is a decision to operate under a different set of requirements. Settle that before building the site.
How to get a straight answer
Call your state department of agriculture and describe the product precisely: low acid ingredients, acidified with vinegar, target pH, shelf stable, sold in these channels. Vague questions get vague answers.
Ask for it in writing or note the name and date. Rules change, staff differ, and a written answer is what you show a retailer who asks.