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95 kPa is a closure test before it is a bottle test.

What is here

163 continuous thread, 44 child resistant, 32 dropper assemblies, 27 spouted, 19 flip top, 14 phenolic, 7 buttress, 6 specialty, 5 dome lids, 3 dropper tips and caps and 3 euro droppers.

The pressure requirement lands here

A container withstanding a 95 kPa differential without leakage is almost always a closure and liner question. The wall rarely fails; the seal does.

Which is why the rule says receptacle or secondary

If the primary closure cannot hold it, the containment moves outward to the secondary packaging. That is a design decision about where the seal lives.

The plain cap is the right closure for a sample

163 continuous thread. No moving parts, nothing to introduce, and opened twice in the life of the container.

Phenolic where something aggressive is inside

14 of them. The traditional resistant closure for a reagent or a solvent, and a small set doing a specific job.

Droppers for reagents, not for specimens

32 assemblies plus 3 tips and 3 euro droppers. A stain or an indicator is dispensed by drop; a specimen is not dispensed at all.

The 44 child resistant closures

Not required by anything in this property. For a reagent kept where people live rather than in a laboratory, it is a reasonable voluntary choice.

Liners are in contact with the contents

For a reagent, a stain or a medium, the liner is a surface the contents touch and it is the component nobody specifies on an order.

And it has to survive the autoclave

A closure cycled to sterilisation temperature repeatedly will deform before the bottle does. For media work the cap is the consumable.

Test the seal the way it will travel

Filled, closed, through a pressure cycle, on its side, warm. That is both the 95 kPa requirement and the ordinary life of a sample in a bag.

References

The Davis Pack Supply catalog, measured 19 October 2026. The diagnostics and lab shelf is 600 rows: 270 containers and 330 closures. 5 mL to 946 mL with a median of 118; 71 containers at 30 mL or under, 105 at 60 or under, 154 at 120 or under, 248 at 500 or under. 154 HDPE, 103 glass, 13 PP, and no PET. 246 bottles, 19 jars, 3 jugs, 2 tubes. 97 white, 57 natural, 35 clear, 28 amber. Closures: 163 continuous thread, 44 child resistant, 32 dropper assemblies, 27 spouted, 19 flip top, 14 phenolic, 7 buttress, 6 specialty, 5 dome lids.
49 CFR 173.199, Category B infectious substances. "A Category B infectious substance must be packaged in a triple packaging consisting of a primary receptacle, a secondary packaging, and a rigid outer packaging." Absorbent material "must be placed between the primary receptacle and secondary packaging" and "must be of sufficient quantity to absorb the entire contents of the primary receptacles". "The primary receptacle or the secondary packaging must be capable of withstanding without leakage an internal pressure producing a pressure differential of not less than 95 kPa." "The packaging must be capable of successfully passing the drop test in 178.609(d) of this subchapter at a drop height of at least 1.2 meters (3.9 feet)." "At least one surface of the outer packaging must have a minimum dimension of 100 mm by 100 mm (3.9 inches)." By aircraft, each primary receptacle may not exceed 1 L and each outer packaging 4 L for liquids, or 4 kg for solids. law.cornell.edu
Written from 49 CFR 173.199 and 173.134, and from the catalog as it stood on 19 October 2026. Nothing here is offered as a compliant primary receptacle for a regulated shipment: the pressure and drop requirements attach to a tested assembly, not to a bottle. Category A infectious substances are a different packaging instruction entirely and are not summarized. Sterility is not claimed for any product, and what a laboratory will accept is the laboratory's to say.